bioinformatics

An open-source search engine helps scientists identify hundreds of microbial metabolites in a matter of seconds. 

Comprehensive genome sequencing of 13,880 tumors revealed somatic and germline mutations that could influence patient treatment and prognosis.

Researchers show how a toxic therapy helped identify a mummy using preserved DNA.

Tumors contain thousands of genetic changes, but only a few are actually cancer-causing. A quicker way to identify these driver mutations could lead to more targeted cancer treatments.

In addition to isolating the first protein-coding gene from a eukaryote, Kedes furthered scientists’ understanding of actin genes and also laid the foundations for modern DNA databases such as GenBank.

The scientific community bid farewell to researchers who furthered the fields of molecular biology, virology, sleep science, and immunology, among others.

Gamze Gursoy and Mark Gerstein of Yale Medical School have developed a strategy for stripping identifying variants from functional genomic data, balancing privacy with utility.

The Johns Hopkins University professor was a co-developer of the Galaxy platform, an open-source bioinformatics tool used in labs around the world.

The MIT associate professor wants to understand microbial communities in their ecological context.

In addition to programs geared towards transforming biologists into bioinformaticians, students need more raw material available for their education.

MinION achieved the longest reads of DNA sequences to date. 

The use of underperforming computational tools is a major offender in science’s reproducibility crisis—and there’s growing momentum to avoid it.

Three methods identify and activate silent bacterial gene clusters to uncover new drugs