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biochemistry

Cluster of red, green, and yellow neurons
The Making of a Memory
Danielle Gerhard, PhD | Jul 1, 2024 | 2 min read
Sheena Josselyn discussed how she uses optogenetic tools to bias, express, and erase memories in mice.
A photo of a scientist placing a sensing lid onto a 96-well microplate before attaching Resipher.
Demystifying Cell Culture Through Oxygen Analysis
The Scientist Staff | Jul 1, 2024 | 1 min read
Walker Inman explains the importance of monitoring cells in culture.
Extracellular vesicle cross-section showing internal and external components
Exploring Extracellular Vesicles: Biomarkers and Beyond
Biotium | 1 min read
Advances in molecular profiling tools and techniques help scientists detect and identify extracellular vesicle markers.
Pieces of cheddar cheese.
How Microbes Craft Cheese Flavors
Mariella Bodemeier Loayza Careaga, PhD | Jul 1, 2024 | 2 min read
Bacterial strains compete and cooperate to make cheddar cheese tasty.
Cartoon of a scientist kneeling over a broken sample tube on the floor.
Crushing ChIP Like Never Before
Shelby Bradford, PhD | Jul 1, 2024 | 2 min read
A wayward lab chair ended three days of work in a single footfall for Elinne Becket.
Fireflies glowing in a dark forest provide a captivating example of the luciferase-catalyzed bioluminescent reaction, which has been harnessed as a powerful research tool.
Luciferase: A Powerful Bioluminescent Research Tool
Priyom Bose, PhD | 9 min read
Luciferase refers to a group of bioluminescence producing enzymes that enable researchers to study gene expression and regulation.
mRNA molecule is manufactured from a ribosome. 
A Twisted Secret that Extends mRNA Longevity in Cells
Maggie Chen | Jun 28, 2024 | 3 min read
By tinkering with branched mRNA structures, scientists lay the groundwork to build better vaccines in the future. 
Image of The 84-Gun Danish Warship "Dronning Marie" in the Sound by Christoffer Wilhelm Eckersberg, a painting that depicts one large and two small Danish ships in the sea.
Uncovering Secrets of Historic Paintings in the Modern Laboratory
Niki Spahich, PhD | Jun 26, 2024 | 6 min read
Heritage scientist Fabiana Di Gianvincenzo uses proteomics to identify protein damage and unusual materials in historic paintings and textiles.
A clear SDS-PAGE gel that contains multiple colored bands. 
Western Blot Protocol, Troubleshooting, and Applications
Rebecca Roberts, PhD | 7 min read
Western blotting allows scientists to identify specific proteins in complex biological samples and determine relative abundance of a protein target.
Infographic showing how the Europa Clipper will characterize many features of the icy moon orbiting Jupiter to determine whether or not it offers a good place to search for life.
Infographic: Exploring Habitability on Europa
Shelby Bradford, PhD | Jun 14, 2024 | 2 min read
Europa Clipper will characterize many features of the icy moon orbiting Jupiter to determine whether or not it offers a good place to search for life.
Rainbow colored DNA strand
Back to the Basics to Break Boundaries
Meenakshi Prabhune, PhD | Jun 14, 2024 | 2 min read
Armed with cutting-edge technologies, scientists find innovative ways to better use biological systems. 
A microscope and a model of a molecule, showcasing the power of atomic force microscopy for surface imaging at atomic resolution.
Atomic Force Microscopy to See the Invisible
Priyom Bose, PhD | 8 min read
Atomic force microscopy (AFM) is a technique for visualizing a variety of samples, from single molecules to living cells, at ultrahigh resolution. 
Molecule of DNA, double helix, 3D illustration
Enzymatic DNA Synthesis: Going to Great Lengths
Danielle Gerhard, PhD | Jun 14, 2024 | 10+ min read
When chemical approaches for synthesizing longer DNA oligonucleotides plateaued, scientists turned to a one-of-a-kind enzyme.
Infographic showing how recombinant proteins usher in an era of sustainable fashion
Infographic: Synthetic Biology is Transforming Clothes and Cosmetics
Meenakshi Prabhune, PhD | Jun 14, 2024 | 2 min read
Recombinant proteins usher in an era of sustainable fashion.
In situ hybridization procedure being conducted in a laboratory.
Tips and Tricks for In Situ Hybridization
Priyom Bose, PhD | 8 min read
In situ hybridization is a powerful molecular technique for detecting and localizing specific nucleic acids in cytological samples. 
Abstract CG background
Synthetic Biology is in Fashion
Meenakshi Prabhune, PhD | Jun 14, 2024 | 10+ min read
Scientists are pulling on the protein threads that bind textiles and cosmetics together.
A chromosome is gradually unwinding until the DNA double helix is visible. Proteins interact with parts of the DNA. Antibodies are attached to these protein-DNA interacting regions.
Chromatin Immunoprecipitation Reveals DNA-Protein Interactions
Mariella Bodemeier Loayza Careaga, PhD | Jun 14, 2024 | 10 min read
Proteins interact with DNA to regulate many vital processes in cells. Nearly 40 years ago, researchers developed a way to map these molecular connections.
Two prairie voles are interacting with one another. The vole on the left sniffs the cheek of the vole on the right.
Be My Vole-entine: How Love and Loss Change the Brain
Paige Nicklas | 4 min read
Neuroscientists studying prairie voles discovered that dopamine in the brain gushes when the animals are with their life partners and that loss of a partner erased this neurochemical signature.
Clipper spacecraft on a flyby over Europas surface.
Europa Clipper Searches for Life's Simple Necessities Beyond the Asteroid Belt
Shelby Bradford, PhD | Jun 14, 2024 | 10+ min read
NASA's upcoming satellite mission will explore the characteristics of Jupiter's ice-crusted moon. Its data will help scientists assess if the icy body has the potential to host life.
Infographic showing the comparison between chemical and enzymatic DNA synthesis
Infographic: Chemical Versus Enzymatic DNA Synthesis
Danielle Gerhard, PhD | Jun 14, 2024 | 2 min read
Polymerase-driven synthesis is gaining traction as scientists look to generate longer oligonucleotides and cut back on hazardous waste.
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