autoimmunity

Carola Vinuesa’s research has illuminated the genetics of lupus and helped to exonerate a mother falsely accused of murdering her four children. 

CD4 T cells mediate gut symptoms that indicate early Parkinson’s disease.

What underlies the uneven burden of autoimmunity between the sexes has remained a mystery. Now, scientists found clues by turning to a key player on the X chromosome.

By editing a mutated immune regulatory gene in patient cells, Rosa Bacchetta brings hope to those suffering from IPEX syndrome.

By editing primary T cells with CRISPR, researchers begin to settle a long-standing debate about a common autoimmunity risk variant.

A therapy for type 1 diabetes is the first to treat patients before symptoms appear, paving the way toward preventing this and other autoimmune diseases.

Staphylococcus aureus appears to be the culprit.

A new study points to repercussions of the Medieval pandemic for the health of modern humans.

Recent studies have lent support for a variety of hypotheses explaining the debilitating symptoms affecting millions of people after SARS-CoV-2 infection.  

Scientists discovered a possibly autoreactive T cell population that forecasts and supports disease progression.

Research traces the evolution of a gene variant that reduces the risk of Alzheimer’s disease, finding that it originally evolved in response to infectious bacteria.

Genetic variants that reduce the editing levels of double-stranded RNA are associated with autoimmune and immune-mediated conditions, a study finds.

Several lines of evidence suggest that targeting the body’s defense pathways might help treat a subset of people with the psychiatric disorder. But many open questions remain.