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Six tubes, each with black dots representing flies, each fly encircled in blue, green, or red.
Combating Age-Related Motor Decline
Increasing levels of the protein Trio preserved synaptic function and motor abilities in aging flies.
Combating Age-Related Motor Decline
Combating Age-Related Motor Decline

Increasing levels of the protein Trio preserved synaptic function and motor abilities in aging flies.

Increasing levels of the protein Trio preserved synaptic function and motor abilities in aging flies.

aging

Three images of a hand with an abrasion progressing from most recently injured (left) to most healed (right).
Stem Cell Plasticity: A Double-Edged Sword
Hannah Thomasy, PhD | Jun 14, 2024 | 5 min read
Yejing Ge explores the behavior of skin-resident stem cells in wound repair, cancer, and aging.
Several X-shaped duplicated chromosomes floating on a blurry blue background.
Centromeres Mutate More Rapidly Than Expected
Kamal Nahas, PhD | May 30, 2024 | 4 min read
After sequencing centromeres in humans and other primates, researchers found that they vary greatly across species and potentially contribute to aging and disease.
Aging and Cancer
Aging and Cancer
Rebecca Roberts, PhD | 6 min read
The relationship between aging and cancer is complex, with several shared underlying mechanisms. 
An artistic illustration of the female reproductive system.
Outsmarting Ovarian Cancer
Mariella Bodemeier Loayza Careaga, PhD | May 8, 2024 | 4 min read
Biochemist Sharon Stack hopes to advance the field of ovarian cancer by exploring the tumor and host-related factors that influence its metastatic process. 
Red and gray round cells floating on a red background. 
Low Intracellular Iron Levels May Keep Blood Stem Cells Young
Alejandra Manjarrez, PhD | Apr 8, 2024 | 3 min read
Removing excess iron from aging mouse blood-forming cells enhances their regenerative capacity.
Cellular Senescence: Why Do Cells Stop Dividing?
Cellular Senescence: Why Do Cells Stop Dividing?
Elina Kadriu | 4 min read
Senescent cells undergo major morphological and metabolic changes when at the end of their lifespan. 
A white and tan mother rat watches over several rat pups. 
Babies on the Brain
Hannah Thomasy, PhD | Apr 1, 2024 | 2 min read
In rats, motherhood leaves long-term biological signatures in a brain region that is crucial for learning and memory.
Illustration of a web of dark blue neurons with a purple glow at the center of each neuron.
How the Brain Hits the Brakes on Aging 
Aparna Nathan, PhD | Mar 18, 2024 | 4 min read
Neurons linked to metabolic processes slow aging in mice.
The fight against time
The Scientist Speaks - The Fight Against Time: Stem Cells and Healthy Aging 
The Scientist | 2 min read
Tricking the body into mimicking a fasting state may hold the key to fighting age-related cognitive decline. 
Back Pain Explained
Rachael Moeller Gorman | Feb 5, 2024 | 4 min read
Not all degenerated intervertebral discs are painful; a new study identified a subset of disc cells that triggers a pathway to pain.
A Molecular Switch for Bone Loss
Mariella Bodemeier Loayza Careaga, PhD | Jan 23, 2024 | 4 min read
Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 
A mole-rat poses in the grass 
The Scientist Speaks - Exploring the Secrets to Longevity and Cancer Resistance in Mole-Rats
The Scientist | 1 min read
Vera Gorbunova discusses what naked and blind mole-rat cells reveal about aging and cancer resistance mechanisms. 
Cropped view of senior man playing with puzzles
A Rare Genetic Mutation Protects Against Alzheimer's Disease
Hannah Thomasy, PhD, Drug Discovery News | Sep 17, 2023 | 4 min read
Data from a highly resilient individual guided researchers to new potential therapeutic targets.
Close up on eyes of mother and daughter faces next to one another
A Long and Unhealthy Life?
Aparna Nathan, PhD | Sep 13, 2023 | 3 min read
A new mouse model shows that the Myc protein has complex effects on aging and cancer.
A person holding a section of his face and looking in to his brain through a magnifying glass stock illustration
Science Philosophy in a Flash - A Look at Aging Through Young Eyes 
Iris Kulbatski, PhD | 1 min read
Aimée Parker shares how her childlike curiosity and collaborative spirit motivate her scientific pursuits.
Melanocyte stem cells are shown in red and other cell nuclei are shown in blue.
Hair Turns Gray Due to Stuck Stem Cells
Mariella Bodemeier Loayza Careaga, PhD | Sep 8, 2023 | 3 min read
Hair-coloring stem cells must swing back and forth between their maturity states to give hair its color.
An elderly person in beige shirt and a knitted, cream-colored vest holds a wooden walking stick.
New Epigenetic Clocks May Confirm Extreme Age
Ida Emilie Steinmark, PhD | Sep 8, 2023 | 4 min read
How will a new version of epigenetic clocks aimed at validating the age of people older than 100 years of age balance accuracy and anonymity?
A Rising Star Launches Brain Power into Outer Space
Science Philosophy in a Flash - A Rising Star Launches Brain Power into Outer Space
Iris Kulbatski, PhD | 1 min read
Alysson Muotri shares how tapping into his inner creative spark fuels his pursuit of science.
Woman smiling at the camera working out on a blue yoga mat.
Keeping Older Muscles Strong
Hannah Thomasy, PhD, Drug Discovery News | Sep 5, 2023 | 5 min read
From stem cell-recruiting gels to hormone cycle restoration, Tracy Criswell has big ideas about how to combat age-related decline in muscle regeneration.
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