Following decades of being called “the powerhouse of the cell,” researchers recently proposed a new description that reflects the multifaceted roles of mitochondria.
In FIRE mice, the lack of microglia causes myelin overgrowth and eventual degeneration, indicating that microglia may contribute to age-related neurodegenerative diseases.
Immune receptor repertoire profiling is an important analytic tool for disease research in many areas, including cancer, cell and organ transplantation, autoimmunity, and infectious disease.
Technological advancements over the last two decades transformed volume electron microscopy, improving usability, resolution, and throughput.
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