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MEGA CRISPR: Engineering Better Immunotherapies with RNA Editing
MEGA CRISPR: Engineering Better Immunotherapies with RNA Editing
Multi-targeted Cas13 screens help researchers avoid permanent DNA cuts and evade T cell exhaustion.
Multi-targeted Cas13 screens help researchers avoid permanent DNA cuts and evade T cell exhaustion.
Cas13
CRISPR Gene Editing: Cas9 and Beyond
Johanna Pruller, PhD and Deanna MacNeil, PhD | Nov 29, 2023 | 7 min read
Researchers create and improve CRISPR-Cas mediated gene editing technologies based on prokaryotic CRISPR systems and eukaryotic DNA repair mechanisms.
The Wonderfully Shrunken Cas13
Rachael Moeller Gorman | Nov 7, 2023 | 3 min read
Scientists removed unnecessary sections of the Cas13 enzyme, creating a mini-enzyme that works and fits with other CRISPR elements into a single gene therapy vector.
Predicting the Next Level of CRISPR Control
Deanna MacNeil, PhD | Aug 28, 2023 | 3 min read
Scientists combine the power of genome-wide screens and machine learning to unlock the secrets of transcriptome engineering with Cas13.
CRISPR System Targets RNA in Mammalian Cells
Anna Azvolinsky | Oct 4, 2017 | 3 min read
Researchers engineer bacterial CRISPR-Cas13 to knock down RNA in mammalian cells.